TRISH is always interested in novel, far-reaching, high-impact proposals to protect and optimize human health and performance during long-duration, deep space exploration missions, such as the mission to Mars. To address this need, TRISH has a standing call for Focused Investigation Projects. The details for this program can be found here.
For guidance regarding concerns of relevant to NASA, the Human Research Roadmap outlines and ranks the risks to humans in long-duration spaceflight.